Comparative Study of Cryotherapy versus Trichloroacetic Acid Chemical Peels in the Treatment of Actinic Keratosis

  • Hawar J. Sabir Dermatology Teaching Center, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region - F.R. Iraq http://orcid.org/0000-0002-6234-6803
  • Intiha M. Ridha Dermatology Teaching Center, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region - F.R. Iraq http://orcid.org/0000-0003-2074-9302
Keywords: Actinic keratosis, Cryotherapy, Squamous cell carcinoma, Trichlororacetic acid

Abstract

Actinic keratosis is cutaneous neoplasm which is including of expansion of cytologically unusual epidermal keratinocytes that grow in response to prolonged exposure to ultraviolet radiation. Since some percentage of actinic keratosis will develop to non-melanoma skin cancers, their treatment is recommended. The study aimed to evaluate the clinical effectiveness of cryotherapy in comparison to topical 25% trichloroacetic acid chemical peels in the treatment of actinic keratosis. A comparative therapeutic study was conducted on forty four patients with actinic keratosis who attended Erbil dermatology teaching center in Erbil city of Kurdistan Region-Iraq. Patients were randomly allocated into two groups: cryotherapy treatment with liquid nitrogen every two weeks and trichloroacetic acid peels every two weeks and the response was controlled on follow up by taking photos. Patient’s age ranged from 40 to 80 years, they were analyzed for 24 weeks. Good response rate was seen in 72.8% of cryotherapy group and 40.9% of trichloroacetic acid group and this was statistically significant (p=0.02).  Cryotherapy was more effective than trichloroacetic acid in the treatment of actinic keratosis.

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Author Biographies

Hawar J. Sabir, Dermatology Teaching Center, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region - F.R. Iraq

Hawar J. Sabir: She got MBChB degree from Hawler Medical University; College of Medicine in 2010.She has five years experience in Dermatology. She participated in many dermatological workshops and international conferences of Dermatology. Now, she is second year trainee of high diploma student at Erbil Dermatology teaching center.

Intiha M. Ridha, Dermatology Teaching Center, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region - F.R. Iraq

Intiha M. Ridha: She got PhD in Dermatology in 1979 from Istanbul University. She has also experienced many training courses; cryotherapy course at England for 3 months, laser treatment at France and many others. She has published many researches. Has attended  most of the international Dermatological conferences and workshops also has carried out many scientific posts; head of Dermatology department at Hawler Medical University for 17 years, has  taken  charge of Dermatology department at ministry of health, head of Dermatology department at Erbil directorate of health.

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Published
2019-06-30
How to Cite
Sabir, H., & Ridha, I. (2019, June 30). Comparative Study of Cryotherapy versus Trichloroacetic Acid Chemical Peels in the Treatment of Actinic Keratosis. UKH Journal of Science and Engineering, 3(1), 59-63. https://doi.org/https://doi.org/10.25079/ukhjse.v3n1y2019.pp59-63
Section
Research Articles