Alterations in the Serum Trace Element Levels in Women Infected with Chlamydia Trachomatis

Authors

DOI:

https://doi.org/10.25079/ukhjse.v4n2y2020.pp65-68

Keywords:

Chlamydia Trachomatis, Trace Elements, Infectious Deseases

Abstract

Most infectious diseases are accompanied by changes in the levels of several trace elements in the blood. A total of 88 female patients referred to the Nawroz Private Laboratory in the Duhok province, Kurdistan Region, Iraq, were enrolled in this study. The enrolled patients were sent to the laboratory for investigation of their hormone levels because they were suffering from various gynecologic abnormalities. The serum levels of anti-chlamydia immunoglobulin (Ig) G and IgM antibodies were estimated using enzyme-linked immunosorbent assay (ELISA) tests, and the serum trace element levels were evaluated by atomic absorption spectroscopy.

The results showed that 10 (11.4 %) of the samples tested positive for the presence of anti-chlamydia IgG antibodies, whereas none of the samples tested positive for anti-chlamydia IgM antibodies. Furthermore, a significant reduction in the serum potassium levels was observed in response to the chlamydia infection, whereas no significant changes were observed in any of the other elements.

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Author Biographies

  • Qais Lazgin Barany, Scientific Research Center, College of Sciences, University of Duhok, Duhok, Kurdistan Region- F. R. Iraq

    Qais Lazgin Barany currently works at the Scientific Research Center, College of Sciences, University of Duhok, Duhok, Kurdistan Region- F. R. Iraq

  • Marwan Khalil Qader, Biology Department- College of Sciences -University of Duhok. Duhok-Kurdistan- F. R. Iraq

    Marwan Khalil Qader: works at Biology Department- College of Sciences -University of Duhok. Duhok-Kurdistan-Iraq. Training in many courses in the field of medical laboratories, Work with many of the competent authorities in the establishment of medical laboratories and in chemical and biological laboratory supplies all of the devices and laboratory materials and chemical origins of various international committees.

  • Ashti Asim Mohamed, Biology Department, College of Sciences, University of Duhok, Duhok, Kurdistan Region- F. R. Iraq

    Ashti Asim Mohamed curretnly works at the Biology Department, College of Sciences, University of Duhok, Duhok, Kurdistan Region- F. R. Iraq

References

Beisel, W. R., Pekarek, R. S., and Wannemacher, R. W. (1974). The impact of infectious diseases on trace element metabolism in the host. In: Hoekstra G, Gauther HE, Mertz W (Eds) Trace element metabolism in animals. University Park Press, Baltimore: 217. 60 (4), July 1976: 831-849

Chandra, R. K. (1984). Excessive intake of zinc impairs immune responses. JAMA. 252: 1443-1446.

Deveci, F. and Ilhan, N. (2003). Plasma malondialdehyde and serum trace element concentrations in patients with active pulmonary tuberculosis. Biological Trace Element Research. 95: 29-38.

Friis, H. (2005). Micronutrients and infections: an introduction. In: Friis, H. ed. Micronutrients and HIV infection. Durban, South Africa. CRC Press: 1-21.

Halme, S.; Latvala, J.; Karttunen, R.; Palatsi, I.; Saikku, P. and Surcel, H. M. (2000). Cell-mediated immune response during primary Chlamydia pneumoniae infection. Infect. Immun. 68: 7156-8.

Kassu, T.; Yabutani, Z. H.; Mahmud, A.; et al. (2006). Alterations in serum levels of trace elements in tuberculosis and HIV infections. European Journal of Clinical Nutrition. 60: 580–586.

Milena L. de Moraes , Catarine G. L. Canellas , Marcelino J. Anjos, Daniela M. P. Ramalho, Karina N. Delogo, Pryscila F. C. Miranda , Eliene D. D. Mesquita, Afrânio L. Kritski , Martha M. Oliveira and Ricardo T. Lopes. (2011). Trace elements status of pulmonary tuberculosis patients compared with healthy voluntarees. International Nuclear Atlantic Conference - INAC 2011 Belo Horizonte,MG, Brazil, October 24-28.

Mohan, G.; Kulshreshtha, S.; and Sharma, P. (2006). Zinc and copper in Indian patients of tuberculosis. Biological Trace Element Research. 111: 63-69.

Paavonen, J. and Eggert-Kruse, W. (1995). Chlamydia trachomatis: impact on human reproduction. Hum Reprod. Update. 5(5):433-47.

Pekarek, R. S. and Engelhardt, J. A. (1981). Infection-induced alterations in trace metal metabolism: Relationship to organism virulence and host defense. 131-146. In Powanda, M.C., Canonico, P.G. (ed.), Infection: The physiologic and metabolic responses of the host. Biomedical Press, Elsevier/North Holland: (131-146).

Scrimshaw, N. S.; Taylor, C. E.; Gordon, J. E. (1968). Interactions of nutrition and infection. Geneva, World Health Organization, 57: pp.329.

Seyrek, A.; Kocyigit, A.; and Erel, O. (2005). Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria. Biol.Trace Elem.Res.106(2): 107-115.

Shankar, A. H. and Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. American Journal of Clinical Nutrition. 68: 447-463.

T Ulukavak Ciftci , B Ciftci, O Yis, Y Guney, A Bilgihan, M Ogretensoy (2003). Changes in serum selenium, copper, zinc levels and Cu/Zn ratio in patients with pulmonary tuberculosis during therapy. Biol. Trace Elem. Res. 95: 65-71.

Tomkins, A. and Watson, F. (1989). Malnutrition and infection. A review. Geneva, ACC/SCN. 5: 136 pp. Geneva (Switzerland).

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Published

2020-12-31

Issue

Vol. 4 No. 2 (2020): ISSUE 7

Section

Research Articles

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How to Cite

Alterations in the Serum Trace Element Levels in Women Infected with Chlamydia Trachomatis. (2020). UKH Journal of Science and Engineering, 4(2), 65-68. https://doi.org/10.25079/ukhjse.v4n2y2020.pp65-68